Location:
Between left atrium and left ventricle; includes posterior and anterior cusps

Function:
Ventricular diastole: open valve allows filling of left ventricle.
Ventricular systole: closed valve prevents reflux from left ventricle to left atrium.

Importance in cardiovascular diseases:
Mitral valve stenosis, mitral valve insufficiency

Importance in device delivery:
Ablation catheter entanglement during retrograde aortic approach for left ventricular and left atrial ablation