Publications
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Original Articles
Pozos RS, Iaizzo PA, Petry RW: Physiological action tremor of the ankle. Journal of Applied Physiology 52: 226-230, 1982.
Iaizzo PA, Pozos RS: Exercise-induced amplitude modification of physiological action tremor of the ankle. Journal of Applied Physiology 53: 1164-1170, 1982.
Quinlan JG, Iaizzo PA, Gronert GA, Taylor SR: Use of dantrolene plus multiple pulses to detect stress-susceptible porcine muscle. Journal of Applied Physiology 60: 1313-1320, 1986.
Iaizzo PA, Klein W, Lehmann-Horn F: Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs. Pflügers Archive, European Journal of Physiology 411: 648-653, 1988.
Iaizzo PA: The effects of temperature on relaxation in frog skeletal muscle: the role of parvalbumin. Pflügers Archive, European Journal of Physiology 412: 195-202, 1988.
Oakes SG, Iaizzo PA, Richelson E, Powis G: Histamine-induced intracellular free Ca++, inositol phosphates and electrical changes in murine N1E-115 neuroblastoma cells. Journal of Pharmacology and Experimental Therapeutics 247: 114-121, 1988.
Quinlan JG, Iaizzo PA, Gronert GA, Lambert EH: Ankle dorsiflexor twitch properties in malignant hyperthermia. Muscle and Nerve 12: 119-125, 1989.
Iaizzo PA, Lehmann-Horn F, Taylor SR, Gallant EM: Malignant hyperthermia: effects of halothane on the surface membrane. Muscle and Nerve 12: 178-183, 1989.
Iaizzo PA, Lehmann-Horn F: The in vitro determination of susceptibility to malignant hyperthermia. Muscle and Nerve 12: 184-190, 1989.
Iaizzo PA, Seewald M, Oakes SG, Lehmann-Horn F: The use of Fura-2 to estimate myoplasmic [Ca2+] in human skeletal muscle. Cell Calcium 10: 151-158, 1989.
Lanier WL, Iaizzo PA, Milde JH: Cerebral function and muscle afferent activity following intravenous succinylcholine in dogs anesthetized with halothane: the effects of pretreatment with a defasciculating dose of pancuronium. Anesthesiology 71: 87-95, 1989.
Lehmann-Horn F, Iaizzo PA: Resealed fiber segments for the study of the pathophysiology of human skeletal muscle. Muscle and Nerve 13: 222-231, 1990.
Iaizzo PA, Lehmann-Horn F: The correlation between electrical after-activity and slowed relaxation in myotonia. Muscle and Nerve 13: 240-246, 1990.
Iaizzo PA, Seewald M, Powis G, Van Dyke RA: The effects of volatile anesthetics on Ca++ mobilization in rat hepatocytes. Anesthesiology 72: 504-509, 1990.
Quinlan JG, Iaizzo PA, Gronert GA, Lambert EH: Twitch responses in a myopathy with impaired relaxation but no myotonia. Muscle and Nerve 13: 326-329, 1990.
Powis G, Seewald MJ, Sehgal I, Iaizzo PA, Olsen RA: Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts. Journal of Biological Chemistry 265: 10266-10273, 1990.
Lehmann-Horn F, Iaizzo PA, Franke C, Hatt H, Spanns F: Schwartz-Jampel syndrome: II. Na+ channel defect causes myotonia. Muscle and Nerve 13: 528-535, 1990.
Franke C, Hatt H, Iaizzo PA, Lehmann-Horn F: Characteristics of Na+ channels and Cl- conductance in resealed muscle fibre segments from patients with myotonic dystrophy. Journal of Physiology (London) 425: 391-405, 1990.
Lanier WL, Iaizzo PA, Milde JH: The effects of intravenous succinylcholine on cerebral function and muscle afferent activity following complete ischemia in halothane-anesthetized dogs. Anesthesiology 73: 485-490, 1990.
Iaizzo PA: Histological and physiological properties of Rana temporaria tibialis anterior and lumbricalis IV muscle fibres. Journal of Muscle Research and Cell Motility 11: 281-292, 1990.
Quinlan JG, Wedel DJ, Iaizzo PA: Multiple-pulse stimulation and dantrolene in malignant hyperthermia. Muscle and Nerve 13: 904-908, 1990.
Iaizzo PA, Olsen RA, Seewald MJ, Powis G, Stier A, Van Dyke RA: Transient increases of intracellular Ca2+ induced by volatile anesthetics in rat hepatocytes. Cell Calcium 11: 515-524, 1990.
Lehmann-Horn F, Iaizzo PA: Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia? British Journal of Anaesthesia 65: 692-697, 1990.
Iaizzo PA, Poppele RE: Twitch relaxation of the cat soleus muscle at different lengths and temperatures. Muscle and Nerve 13: 1105-1112, 1990.
Olsen RA, Seewald MJ, Melder DC, Berggren M, Iaizzo PA, Powis G: Platelet-derived growth factor blocks the increase in intracellular free Ca2+ caused by calcium ionophores and a volatile anesthetic agent in Swiss 3T3 fibroblasts without altering toxicity. Toxicology Letters 55: 117-125, 1991.
Wedel DJ, Iaizzo PA, Milde JH: Desflurane is a trigger of malignant hyperthermia in susceptible swine. Anesthesiology 74: 508-512, 1991.
Iaizzo PA, Seewald MJ, Olsen R, Wedel DJ, Chapman DE, Berggren M, Eichinger HM, Powis G: Enhanced mobilization of intracellular Ca2+ induced by halothane in hepatocytes isolated from swine susceptible to malignant hyperthermia. Anesthesiology 74: 531-538, 1991.
Iaizzo PA, Franke C, Hatt H, Spittelmeister W, Ricker K, R üdel R, Lehmann-Horn F: Altered sodium channel behaviour causes myotonia in dominantly inherited myotonia congenita. Neuromuscular Disorders 1: 47-53, 1991.
Lehmann-Horn F, Iaizzo PA, Hatt H, Franke C: Altered gating and conductance of Na+ channels in hyperkalemic periodic paralysis. Pflügers Archive, European Journal of Physiology 418: 297-299, 1991.
Seewald M, Eichinger HM, Lehmann-Horn F, Iaizzo PA: Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques. Acta Anaesthesiologica Scandinavica 35: 345-349, 1991.
Seewald M, Eichinger HM, Iaizzo PA: Malignant hyperthermia: an altered phospholipid and fatty acid composition in muscle membranes. Acta Anaesthesiologica Scandinavica 35: 380-386, 1991.
Franke C, Iaizzo PA, Hatt H, Spittelmeister W, Ricker K, Lehmann-Horn F: Altered Na+ channel activity and reduced Cl- conductance cause hyperexcitability in recessive generalized myotonia (Becker). Muscle and Nerve 14: 762-770, 1991.
Iaizzo PA, Wedel DJ, Gallagher WJ: In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodological update. Mayo Clinic Proceedings 66: 998-1004, 1991.
Pozos RS, Iaizzo PA: Shivering and pathological and physiological clonic oscillations of the human ankle. Journal of Applied Physiology 71: 1929-1932, 1991.
Lanier WL, Iaizzo PA, Murray MJ: The effects of convective cooling and rewarming on systemic and central nervous system physiology in isoflurane-anesthetized dogs. Resuscitation 23: 121-136, 1992.
Iaizzo PA: The effects of halothane and isoflurane on intracellular Ca2+ regulation in cultured cells with characteristics of vascular smooth muscle. Cell Calcium 13: 513-520, 1992.
Iaizzo PA, Pozos RS: Analysis of multiple EMG and acceleration signals of various record lengths as a means to study pathological and physiological oscillations. Electromyography and Clinical Neurophysiology 32: 359-367, 1992.
Pozos RS, Iaizzo PA: Effects of topical anesthesia on essential tremor. Electromyography and Clinical Neurophysiology 32: 369-372, 1992.
Deufel T, M üller-Felber W, Pongratz DE, H übner G, Johnson K, Iaizzo PA, Lehmann-Horn F: Chronic myopathy in a patient suspected of carrying two malignant hyperthermia susceptibility (MHS) mutations. Neuromuscular Disorders 2: 389-396, 1992.
Iaizzo PA, Seewald MJ, Powis G, Van Dyke RA: The effects of sevoflurane on intracellular Ca2+ regulation in rat hepatocytes. Toxicology Letters 66: 81-88, 1993.
Zink RS, Iaizzo PA: Convective warming therapy does not increase the risk of wound contamination in the operating room. Anesthesia and Analgesia 76: 50-53, 1993.
Seewald MJ, Iaizzo PA, Heisswolf E, Eichinger HM: Effects of meat quality and storage on the breakdown of adenosine triphosphate in muscle from swine. Meat Science 35: 47-61, 1993.
Wedel DJ, Gammel SA, Milde JH, Iaizzo PA: Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine. Anesthesiology 78: 1138-1144, 1993.
Otten W, Wirth C, Iaizzo PA, Eichinger HM: A high omega 3 fatty acid diet alters the fatty acid composition of heart, liver, kidney, adipose tissue and skeletal muscle in swine. Annals of Nutrition and Metabolism 37: 134-141, 1993.
Beebe DS, Gauthier RL, DeMars JJ, Iaizzo PA: Lower extremity hypothermia is beneficial during infra-renal aortic cross-clamping in pigs. Anesthesia and Analgesia 77: 241-249, 1993.
Lanier WL, Iaizzo PA, Milde JH, Sharbrough FW: The cerebral and systemic effects of movement in response to a noxious stimulus in lightly anesthetized dogs. Possible modulation of cerebral function by muscle afferents. Anesthesiology 80: 392-401, 1994.
Iaizzo PA, Wedel DJ: Response to succinylcholine in porcine malignant hyperthermia. Anesthesia and Analgesia 79: 143-151, 1994
Yamada H, Transfedt EE, Tamaki T, Torres F, Iaizzo PA: The effects of volatile anesthetics on the relative amplitudes and latencies of spinal and muscle potentials evoked by transcranial magnetic stimulation. Spine 19: 1512-1517, 1994.
Iaizzo PA, Quasthoff S, Lehmann-Horn F: Differential diagnosis of periodic paralysis aided by in vitro myography. Neuromuscular Disorders 5: 115-124, 1995.
Wedel DJ, Quinlan JG, Iaizzo PA: Clinical effects of therapeutic levels of dantrolene. Mayo Clinic Proceedings 70: 241-246, 1995.
Yamada H, Transfeldt EE, Tamaki T, Nishiura H, Taylor BA, Torres F, Iaizzo PA: General anesthetic effects on compound muscle action potentials elicited by single or dual spinal stimulation. Journal of Spinal Disorders 8: 157-162, 1995.
Lerche H, Fahlke C, Iaizzo PA, Lehmann-Horn F: Characterization of the high-conductance Ca2+-activated K+ channel in adult human skeletal muscle. Pfl ügers Archive, European Journal of Physiology 429: 738-747, 1995.
Verhaegen M, Iaizzo PA, Todd MM: A comparison of the effects of hypothermia, pentobarbital and isoflurane on cerebral energy stores at the time of ischemic depolarization. Anesthesiology 82: 1209-1215, 1995.
Kokate JY, Leland KJ, Held AM, Hansen GL, Kveen GL, Johnson BA, Wilke MS, Sparrow EM, Iaizzo PA: Temperature-modulated pressure ulcers: a porcine model. Archives of Physical Medicine and Rehabilitation 76: 666-673, 1995
Hofer RE, Lanier WL, Iaizzo PA: The temporal relationship between intraocular pressure and extraocular muscle activation in cats. Pfl ügers Archive, European Journal of Physiology 430: 779-786, 1995.
Iaizzo PA, Kveen GL, Kokate JY, Leland KJ, Hansen GL, Sparrow EM: Prevention of pressure ulcers by focal cooling: histological assessment in a porcine model. Wounds: A Compendium of Clinical Research and Practice 7: 161-169, 1995.
Lanier WL, Albrecht RF, Iaizzo PA: Divergence of intracranial and central venous pressures in lightly anesthetized, tracheally intubated dogs that move in response to a noxious stimulus. Anesthesiology 84: 605-613, 1996.
Iaizzo PA, Kehler CH, Zink RS, Belani KG, Sessler DI: Thermal response in acute porcine malignant hyperthermia. Anesthesia and Analgesia 82: 782-789, 1996.
Iaizzo PA, Kehler CH, Carr RJ, Sessler DI, Belani KG: Prior hypothermia attenuates malignant hyperthermia in susceptible swine. Anesthesia and Analgesia 82: 803-809, 1996.
Brass TJ, Loushin MK, Day JW, Iaizzo PA: An improved method for muscle force assessment in neuromuscular disease. Journal of Medical Engineering and Technology 20: 67-74, 1996.
Hansen GL, Sparrow EM, Kammamuri R, Iaizzo PA: Assessing wound severity using color and infrared imaging of reactive hyperemia. Wound Repair and Regeneration 4: 386-392 1996.
Janke AW, Kerkow TA, Griffiths HJ, Sparrow EM, Iaizzo PA: The biomechanics of gravity-dependent traction of the lumbar spine. Spine 22: 253-260, 1997.
Hansen GL, Sparrow EM, Kokate JY, Leland KJ, Iaizzo PA: Wound status evaluation using color image processing. IEEE Transactions on Medical Imaging 16: 78-86, 1997.
Hartmann S, Otten W, Kratzmair M, Seewald MJ, Iaizzo PA, Eichinger HM: Influences of breed, sex, and susceptibility to malignant hyperthermia on lipid composition of skeletal muscle and adipose tissue in swine. American Journal of Veterinary Research 58: 738-743, 1997.
Otten W, Iaizzo PA, Eichinger HM: Effects of a high n-3 fatty acid diet on membrane lipid composition of heart and skeletal muscle in normal swine and in swine with the genetic mutation for malignant hyperthermia. Journal of Lipid Research 38: 2023-2034, 1997.
Kokate JY, Leland KJ, Sparrow EM, Iaizzo PA: Critical thresholds for pressure ulcer formation in a porcine model. Wounds: A Compendium of Clinical Research and Practice 9: 111-121, 1997.
Chen MFf, Niggeweg R, Iaizzo PA, Lehmann-Horn F, Jockusch H: Chloride conductance in mouse muscle is subject to post-transcriptional compensation of the functional C1- channel 1 gene dosage. Journal of Physiology 504: 75-81, 1997.
Hansen GL, Sparrow EM, Kalieta AL, Iaizzo PA: Using infrared imaging to assess the severity of pressure ulcers. Wounds: A Compendium of Clinical Research and Practice 10: 43-53, 1998.
Podein RJ, Iaizzo PA: Applied forces and associated physiological responses induced by axial spinal unloading with the LTX 3000TM Lumbar Rehabilitation System. Archives of Physical Medicine and Rehabilitation 79: 505-513, 1998.
McLoon LK, Falkenberg JH, Dykstra D, Iaizzo PA: Doxorubicin chemomyectomy as a treatment for cervical dystonia: histological assessment after direct injections into the sternocleidomastoid muscle. Muscle and Nerve 21: 1457-1464, 1998.
Sigg DC, Houlton AJ, Iaizzo PA: The potential for increased risk of infection due to the reuse of convective air-warming/cooling coverlets. Acta Anaesthesia Scandinavica 43: 173-176, 1999.
Shailesh Kumar MV, Carr RJ, Komanduri V, Reardon RF, Beebe DS, Iaizzo PA, Belani KG: Differential diagnosis of thyroid crisis and malignant hyperthermia in an anesthetized porcine model. Endocrine Research 25: 87-103, 1999.
Iaizzo PA, Johnson BA, Nagao K, Gallagher WJ: 4-Chloro-m-cresol triggers malignant hyperthermia in susceptible swine at doses greatly exceeding those found in drug preparations. Anesthesiology 90: 1723-1732, 1999.
Musley, SK, Beebe DS, Komanduri V, Iaizzo PA, Belani KG: Hemodynamic and metabolic manifestations of acute endotoxin infusion in pigs with and without the malignant hyperthermia mutation. Anesthesiology 91: 833-838, 1999.
Iaizzo PA, Jeon YM, Sigg DC: Facial warming increases the threshold for shivering. Journal of Neurosurgical Anesthesiology 11: 231-239, 1999.
Brinkmeier H, Krämer J, Krämer R, Iaizzo PA, Baur C, Lehmann-Horn F, Rüdel R: Malignant hyperthermia causing Gly2435Arg mutation of the ryanodine receptor facilitates ryanodine-induced calcium release in myotubes. British Journal of Anaesthesiology 83: 855-861, 1999.
McLoon LK, Iaizzo PA, Falkenberg JH, Dykstra D:
In vitro physiological assessment of muscle strength after direct
injection of doxorubicin into rabbit sternocleidomastoid muscle,
Muscle and Nerve 22: 652-653, 1999.
Sigg DC, Iaizzo PA: Malignant hyperthermia phenotype: hypotension induced by succinylcholine in susceptible swine. Anesthesiology 92: 1777-1788, 2000.
Jurkat-Rott K, Mitrovic N, Hang C, Kouzmekine A, Iaizzo PA, Herzog J, Lerche H, Nicole S, Vale-Santos J, Chauveau D, Fontaine B, Lehmann-Horn F: Voltage-sensor sodium channel mutations cause hypokalemic periodic paralysis type 2 by enhanced inactivation and reduced current. Proceedings of National Academy of Science, 97: 9549-9554, 2000.
Chinchoy E, Soule CL, Houlton AJ, Gallagher WJ, Hjelle MA, Laske TG, Morissett J, Iaizzo PA: Isolated four-chamber working swine heart model. Annals of Thoracic Surgery 70: 1607-1614, 2000.
Thompson MD, Gallagher WJ, Iaizzo PA, Lanier WL: The effect of chronic dexamethasone-induced hyperglycemia, and its acute treatment with insulin on brain glucose and glycogen concentrations in rats. Anesthesiology 93: 1279-1284, 2000.
Harlow HJ, Lohuis T, Beck TD, Iaizzo PA: Muscle strength in overwintering bears. Nature 409: 997, 2001.
Falkenberg J, Iaizzo PA, McLoon LK: Physiological assessment of muscle strength in vitro after direct injection of doxorubicin into rabbit sternocleidomastoid muscle. Movement Disorders 16: 683-692, 2001.
Sweney MT, Sigg DC, Tahvildari S, Iaizzo PA: Shiver suppression using focal hand warming in unanesthetized normal subjects. Anesthesiology 95: 1089-1095, 2001.
Falkenberg J, Podein RJ, Pardo X, Iaizzo PA: Surface EMG activity of the back musculature during axial spinal unloading using an LTX 3000TM Lumbar Rehabilitation System. Electromyography and Clinical Neurophysiology 41: 419-427, 2001.
Sigg, DC, Coles JA Jr, Gallagher WJ, Oeltgen PR, Iaizzo PA: Opioid preconditioining: myocardial function and energy metabolism. The Annals of Thoracic Surgery, 72: 1576-1582, 2001.
Hales J, Larson P, Iaizzo PA: Treatment of adult lumbar scoliosis with axial spinal unloading using the LTX3000TM Lumbar Rehabilitation System. Spine 27: E71-79, 2002.
Day JW, Sakamoto C, Parry GJ, Lehmann-Horn F, Iaizzo PA: Force assessment in periodic paralysis after electrical muscle stimulation. Mayo Clinic Proceedings 77: 232-240, 2002.
Cardozo RN, Durfee WK, Ardichwili A, Adams C, Erdman AG, Hoey M, Iaizzo PA, Mallick D, Bar-Cohen A, Beachy R, Johnson A: Experiential education in new product design and business development. Journal of Product Innovation Management 19(1):4-17, 2002.
Hong J, Iaizzo PA: Force assessment of the stimulated arm flexors: quantification of contractile propoerties. Journal of Medical Engineering & Technology 26:28-35, 2002.
Falkenberg JH, Iaizzo PA, McLoon LK: Muscle strength following direct injection of doxorubicin into rabbit sternocleidomastoid muscle in situ. Muscle and Nerve, 25: 735-741, 2002.
Sigg, D, Coles JA Jr, Oeltgen P, Iaizzo PA: Role of delta-opioid receptors on infarct size reduction in swine. American Journal of Physiology: Heart and Circulatory. 282: H1953-1960, 2002.
Lahm R, Iaizzo PA: Physiologic responses during rest on a sleep system at varied degrees of firmness in a normal population. Ergonomics 45: 798-815, 2002.
Schulte-Mattler WJ, Müller T, Deschauer M, Gellerich FN, Iaizzo PA, Zierz S: Increased metabolic muscle fatigue is caused by some but not all mitochondrial mutations. Archives of Neurology 60: 50-58, 2003.
Christiansen SP, Becker BA, Iaizzo PA, McLoon LK: Extraocular muscle force generation after Ricin-m-Ab35 injection: implications for strabismus treatment. Investigative Ophthalmology & Visual Science (in press) 2003.
Coles JA Jr, Sigg, D, Iaizzo PA: Role of kappa-opioid receptor activation in pharmacological preconditioning in swine. American Journal of Physiology: Heart and Circulatory 284:2091-2099, 2003.
Hilse MA, Erdman AG, Iaizzo PA: Axial unloading therapy device for cervical spine rehabilitation. Journal of Medical Engineering & Technology 27: 207-217, 2003.
Hill A, Coles JA Jr, Sigg DC, Laske, TG, Iaizzo PA: Images of the human coronary sinus ostium obtained from isolated working hearts. The Annals of Thoracic Surgery 76: 2108, 2003.
He X, McGee S, Coad JE, Schmidlin F, Iaizzo PA, Swanlund DJ, Kluge S, Rudie E, Bischof JC: Investigation of the thermal and tissue injury behavior in microwave thermal therapy using a porcine kidney model International Journal of Hyperthermia 20: 567-593, 2004.
Ginz HF, Zorzato F, Iaizzo PA, Urwyler A: Effect of three anaesthetic techniques on isometric skeletal muscle strength. British Journal of Anaesthesia 92: 367-372, 2004.
Iaizzo, PA: Temperature modulation of pressure ulcer formation: Using a swine model . WOUNDS: A Compendium of Clinical Research and Practice 16: 336-343, 2004.
Hong J, Falkenberg JH, Iaizzo PA: Stimulated muscle force assessment of the sternocleidomastoid muscle in humans. Journal of Medical Engineering & Technology 29: 82-89, 2005.
Hill AJ, Laske TG, Coles JA Jr, Sigg DC, Skadsberg ND, Vincent SA, Soule CL, Gallager WJ, Iaizzo PA: In vitro studies of human hearts. The Annals of Thoracic Surgery 79: 168-177, 2005.
Hong J, Sigg DC, Coles JA JR, Oeltgen PR, Harlow HJ, Soule CL,
Iaizzo PA: Hibernation induction trigger reduces
hypoxic damage of swine skeletal muscle. Muscle & Nerve
32; 200–207, 2005.
Coles JA Jr, Sigg DC, Iaizzo PA: The potential benefits of 1.5% hetastarch as a cardioplegia additive. Biochemical Pharmacology 69: 1553-1558, 2005.
Laske TG, Vincent SA, Skadsberg ND, Iaizzo PA:
High pacing impedances: Are you overtorquing your leads? Pacing
and Clinical Electrophysiology 28: 883-891, 2005.
Laske TG, Skadsberg ND, Iaizzo PA: A novel ex
vivo heart model for the assessment of cardiac pacing systems. Journal
of Biomechanical Engineering 127:894-898, 2005.
Laske TG, Harlow HJ, Werder JC, Marshall MT, Iaizzo PA:
High capacity implantable data recorders: System design and experience
in canines and denning black bears. Journal of Biomechanical Engineering
127: 964-971, 2005.
Ginz HF, Iaizzo PA, Girard T, Urwyler A, Pargger
H: Decreased isometric skeletal muscle force in critically ill patients.
Swiss Medical Weekly 135:555-561, 2005.
Laske TG, Skadsberg ND, Hill AJ, Iaizzo PA: Excitation
of the intrinsic conduction system through His and interventricular
septal pacing. Pacing and Clinical Electrophysiology 29:397-405,
2006.
Snedeker JG, Barnstuble BB, Iaizzo PA, Farshad
M, Niederer P, Schmidlin FR: A comprehensive renal injury concept
based on a validated finite element model of the human abdomen.
Journal of Trauma, Injury, Infection, and Critical Care 62:1240-9,
2007.
Lohuis T, Harlow HJ, Beck TdI, Iaizzo PA: Hibernating
bears conserve muscle strength and maintain fatigue resistance.
Physiological and Biochemical Zoology 80:257-69, 2007.
Sola S, Garshelis DL, Amaral JD, Noyce KV, Coy PL, Steer CJ, Iaizzo
PA, Rodrigues CMP: Plasma levels of ursodeoxycholic acid
in black bears, Ursus americanus: seasonal changes. Comparative
Biochemistry and Physiology 143:204-208, 2006.
Xiao YF, TenBroek EM, Wilhelm JJ, Iaizzo PA, Sigg
DC: Electrophysiological characterization of murine HL-5 atrial
cardiomyocytes. AJP: Cell Physiology 291:C407-416, 2006.
Hill AJ, Ahlberg SE, Wilkoff BL, Iaizzo PA: Dynamic
obstruction to coronary sinus access: the Thebesian valve. Heart
Rhythm 3:1240-1, 2006.
Sigg DC, Iaizzo PA: In vivo versus in vitro comparison
of swine cardiac performance: Induction of cardiodepression with
halothane. European Journal of Pharmacology 543:97-107, 2006.
Chromy CA, Carey MT, Balgaard KG, Iaizzo PA: The
potential use of axial spinal unloading in the treatment of adolescent
idiopathic scoliosis: A case series. Archive of Physical Medicine
and Rehabilitation 87:1447-53, 2006.
Ahlberg SE, Ripplinger CM, Skadsberg ND, Iaizzo PA,
Mulligan L: Effects of pacing rate on mechanical restitution within
the in vivo canine heart: Study of the force-frequency relationship.
Journal of Cardiovascular Electrophysiology 18:212-7, 2007.
Shrivastav M, Iaizzo PA: In vivo cardiac monophasic
action potentials recorded using electromyogram needles. IEEE (in
press) 2007.
Bischoff TC, Martens MD, Adams MH, Gallagher WJ, Iaizzo
PA: Measurement of impact loads applied to an implanted
drug pump connector in a porcine cadaver specimen. Journal of Medical
Devices (in press) 2007.
Lü, F, Iaizzo PA, Benditt DG, Mehra R, Warman
EN, McHenry BT: Isolated atrial segment pacing: an alternative to
His bundle pacing after atrioventricular junctional ablation. Journal
of the American College of Cardiology 49:1443-9, 2007.
Ahlberg SE, Hamlen RC, Ewert DL, Iaizzo PA, Mulligan
LJ: Novel means to monitor cardiac performance: the impact of the
force-frequency and force-interval relationships on recirculation
fraction and potentiation ratio. Cardiovascular Engineering 2007
Feb 22; [Epub ahead of print].
Shrivastav M, Shrivastav R, Iaizzo PA: Following
the beat of cardiac potentials. IEEE Potentials (in press) May/June
2007.
Anderson SE, Skadsberg ND, Laske TG, Benditt DG, Iaizzo
PA: Variation in pacing impedance: impact of implant site
and measurement method. PACE (in press) 2007.
Ginz HF, Iaizzo PA, Urwyler A, Pargger H: Use of
non-invasive stimulation muscle force assessment in long-term critically
ill patients: a future standard in the intensive care unit? Acta
Anaesthesiologica Scandinavica (in press) 2007.
Ahlberg SE, Grenz NA, Ewert DL, Iaizzo PA, Mulligan
LJ: Effect of pacing site on systolic mechanical restitution curves
in the in vivo canine model. Cardiovascular Engineering (in press)
2007.
Review Articles
Iaizzo PA, Palahniuk RJ: Malignant hyperthermia: diagnosis, treatment, genetics and pathophysiology. Investigative Radiology 26:1013-1018, 1991.
Iaizzo PA, Palahniuk RJ, Cameron CB, Belani KG: Malignant hyperthermia. Journal of Anaesthesiology - Clinical Pharmacology 9:95-104, 1993.
Sigg DC, Hasinoff IK, Iaizzo PA: Prolonged paralysis and muscular weakness in critically ill patients; Part I. The American Journal of Anesthesiology 27:265-272, 2000.
Sigg DC, Hasinoff IK, Iaizzo PA: Prolonged paralysis and muscular weakness in critically ill patients: Part II. Neuromuscular blockers. The American Journal of Anesthesiology 27:321-328, 2000.
Mallick DN, Adams C, Durfee WK, Erdman A, Iaizzo PA: An experiential approach to preparing students for leadership in managing technology. Decision Line, pp. 4-22, July 2004
Books
Iaizzo PA (Editor). The Handbook of Cardiac Anatomy, Physiology and Devices. Humana Press Inc., Totowa, New Jersey 2005
Book Chapters
Pozos RS, Iaizzo PA, Danzl DF, Mills W III: Limits of tolerance to cold. In: Handbook of Physiology: Environmental Physiology, Fregly MJ, Blatteis CM (eds.) Oxford University Press, Chapter 25, pages 557-578, 1996.
Iaizzo PA, Day JW: The potential for anesthetic complications in patients with muscle disorders. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume X, Chapter 9, pages 151-172, 1996.
Iaizzo PA: Methods for monitoring modulations in intracellular [Ca2+]. In: Anesthesia: Biological Foundations, Yaksh TL, Lynch C III, Zapol WM, Maze M, Biebuyck JF, Saidman LJ (eds.), Raven Press, New York, Chapter 24, pages 399-415, 1997.
Sigg D, Hasinoff IK, , Iaizzo PA: Weakness in the ICU paralysis syndrome: differential diagnosis. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XII, Chapter 8, pages 127-156, 1998.
Sigg D, Hausmann ON, Falkenberg JH, Iaizzo PA: Low back pain, part I: physiology and pathophysiology. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XIV, Chapter 8, pages 115-128, 2000.
Sigg D, Hausmann ON, Falkenberg JH, Iaizzo PA: Low back pain, part II: differential diagnoses and patient evaluation. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XIV, Chapter 10, pages 151-164, 2000.
Sigg D, Hausmann ON, Falkenberg JH, Iaizzo PA: Low back pain, part III: treatment approaches. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XIV, Chapter 12, pages 183-200, 2000.
Iaizzo PA: Malignant hyperthermia: blood and blood flow. In: Malignant Hyperthermia, Schulte am Esch J, Scholz J, Wappler F (eds.), Pabst Science Publishers, pages 148-153, 2000.
Coles JA Jr, Sigg DC, Bittner HB, Iaizzo PA: Surgical myocardial protection: Part I. Physiological basis and clinical relevance. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XVI, Chapter 3, pages 35-48, 2002.
Sigg, DC, Coles JA, Iaizzo PA: Surgical myocardial protection: Part II. From ischemic preconditioning to gene therapy: emerging experimental cardioprotective approaches. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XVI, Chapter 5, pages 63-80, 2002.
Iaizzo PA: General features of the cardiovascular system. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 1, pages 3-11, 2005.
Hill AJ, Iaizzo PA: Comparative cardiac anatomy. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 5, pages 81-91, 2005.
Lahm R, Iaizzo PA: The coronary system and associated medical devices. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 6, pages 93-100, 2005.
Chinchoy E, Ujhelyi M, Hill AJ, Skadsberg ND, Iaizzo PA: The pericardium. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 7, pages 101-110, 2005.
Laske, TG, Iaizzo PA: The cardiac conduction system. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 9, pages 123-136, 2005.
Fitzgerald K, Iaizzo PA: Autonomic nervous system. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 10, pages 137-148, 2005.
Coles JA Jr, Sigg DC, Iaizzo PA: Reversible and irreversible damage of the myocardium: new ischemic syndromes, ischemia/reperfusion injury, and cardioprotection. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 12, pages 161-170, 2005.
Dupre A, Vincent S., Iaizzo PA: Basic ECG theory, recordings and interpretation. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 15, pages 191-201, 2005.
Loushin MK, Iaizzo PA: Mechanical aspects of cardiac performance. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 16, pages 203-222, 2005.
McManus D, Mahre MA, Iaizzo PA: Historical perspective of cardiovascular devices and techniques. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 20, pages 273-285, 2005.
Laske TG, Legreid A, Iaizzo PA: Pacing and defibrillation. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 23, pages 323-348, 2005.
Skadsberg ND, Laske TG, Iaizzo PA: Cardiac mapping systems. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 25, pages 361-369, 2005.
Iaizzo PA: Emerging cardiac devices and technologies.
In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana
Press, Chapter 33, pages 445-457, 2005.
Durfee WK and Iaizzo PA: Rehabilitation and Muscle
Testing. In: Encyclopedia of Medical Devices and Instrumentation,
Second Edition. John Wiley & Sons, pages 62-71, 2006.
Invited Articles
Pozos RS, Stauffer EK, Iaizzo PA, Mills W, Howard
D, Israel D: Shivering and other forms of tremor. In: Living in
the Cold. Heller E (ed.), Elseveir Press, North Holland, Amsterdam,
pp. 531-537, 1986.
Eichinger H, Seewald M, Iaizzo PA: Membrane phospholipid concentrations in cardiac and skeletal muscles from normal and malignant hyperthermia susceptible pigs. In: Control and Regulation of Animal Growth. Quirke JF and Schmid H (eds.), EAAP Pub. No. 36, Pudoc, Wageningen, Netherlands, pp. 191-200, 1988.
Iaizzo PA: The pathophysiology of malignant hyperthermia. Acta Anaesthesiologica Scandinavica 33:45-47, 1989.
Lehmann-Horn F, Iaizzo PA: Physiologie der menschlichen skelettmuskulatur: Ergebnisse an routinemäßig entnommenen muskelproben. In: Malignant Hyperthermia. Mauritz W, Bergmann H, Steinbereithner K (eds.). Beiträge zur Anaesthesiiologie unt Intensivmedizin 27:19-23, 1989.
Lehmann-Horn F, Iaizzo PA: Use of fiber segments to investigate the pathophysiology of human skeletal muscle. In: Advances in Neuromuscular Diseases. Serratrice G, Pellissier JF, Desnuelle C, Pouget J (eds.), Expansion Scientifique Francaise, pp. 44-50, 1989.
Lehmann-Horn F, Iaizzo PA: Neuromuscular diseases and their relationship to malignant hyperthermia. In: Advances in Neuromuscular Diseases. Serratrice G, Pellissier JF, Desnuelle C, Pouget J (eds.), Expansion Scientifique Francaise, pp. 260-266, 1989.
Iaizzo PA, Klein W, Lehmann-Horn F: Myoplasmic calcium and contractures in MH susceptible skeletal muscle. In: Malignant Hyperthermia, An Update. Proceedings of the VI Myology Colloquium. Hofmann JG, Schmidt A (eds.), Volk and Gesundheit, Berlin, pp. 247-252, 1989.
Lehmann-Horn F, Klein W, Hohne E, Iaizzo PA: In vitro diagnosis of susceptibility to malignant hyperthermia. In: Malignant Hyperthermia, An Update. Proceedings of the VI Myology Colloquium. Hofmann JG, Schmidt A (eds.), Volk and Gesundheit, Berlin, pp. 97-100, 1989.
Eichinger HM, Seewald MJ, Iaizzo PA: Porcine malignant hyperthermia: new insights into the pathophysiology as it may relate to meat quality. In: Proceedings Vol. III ICOMST. Copenhagen, Denmark, pp. 1119-1123, 1989.
Lehmann-Horn F, Iaizzo PA, Franke Ch: Hyperexcitability of muscle fibers in Schwartz-Jampel syndrome. In: The Motor Unit: Physiology, Diseases, Regeneration. Dengler R (ed.), Urban and Schwarzenberg, München, FRG, pp. 63-70, 1990.
Lehmann-Horn F, Franke Ch, Iaizzo PA, Klein W, Spieß-Kiefer C: Erkrankungen der Skelett Muskulatur. In: Entwicklungen in der Neurologie. Struppler A, Dengler R (eds.), TM-Verlag, Hameln, pp. 25-29, 1990.
Wagner A, Iaizzo PA, Lehmann-Horn F: Relationship between electrical and mechanical muscle activity in myotonia. Psychiatry Neurology and Medical Psychology 42:569-575, 1990.
Seewald MJ, Eichinger HM, Powis G, Iaizzo PA: Halothane and putative second messenger agents enhance the release of intracellular Ca2+ in hepatocytes prepared from swine susceptible to malignant hyperthermia. Meat Science and Technology 1:473-476, 1991.
Lehmann-Horn F, Spittlemeister W, Iaizzo PA, Franke Ch: Veränderrungen der Muskelzellmembran bie Myotoner Dystrophie. In: Diagnosis und Therapieansätze Dei Neuromuskulären Krankhelten. Kunze K, Arct A, Thayssen G (eds.), Gustav Fisher Verlag, Stuttgart, pp. 38-43, 1992.
Iaizzo PA: The physiology and biochemistry of skeletal muscle and its correlates to malignant hyperthermia. In: Anaesthesia and Pharmacogenetic Diseases: Malignant Hyperthermia. Minerva Anaesthesiologica 60:131-136, 1994.
Iaizzo PA, Held AM, Zink RS, Williams GW, Leon AS, Palahniuk RJ: Exercise-induced heat stress: passive recovery or subsequent treatment. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pp. 8-9, 1994.
Shireman BL, Oakes SG, Iaizzo PA, Sparrow EM: Laboratory simulations of air jet dynamics found in forced-air warming systems. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pp. 152-153, 1994.
Seiffert DJ, Oakes SG, Ziaimehr H, Stapf D, Iaizzo PA, Sparrow EM: A thermoelectric-based forced -air delivery system to induce controlled changes in body temperatures. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pp. 118-119, 1994.
Shireman BL, Oakes SG, Iaizzo PA, Sparrow EM: A heat flux mannequin instrumented with 28 thermal guarded calorimeters. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pp. 180-181, 1994.
Kokate J, Leland K, Johnson BA, Kveen G, Oakes SG, Sparrow EM, Iaizzo PA: Thermoregulation of the skin in a porcine model. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pp. 158-159, 1994.
Iaizzo PA: Assessment of stimulated muscle force in humans. In: Proceedings of the Tage der Electrotechnik der Fachhochschule Anhalt. Hoffmann K-P, Weber B (eds.), pp. 1-11,1997.
Schulte-Mattler WJ, Iaizzo PA: NIR-Spektroskopie und stimulierte Kraftmessung. Proceedings of the Tage der Elektrotechnik der Fachhochschule Anhalt. Hoffman KP, Weber B (Hrsg.), 1998.
Iaizzo PA, Laske TG: The Visible Heart™: The collaborative development and use of this educational tool by the University of Minnesota and Medtronic. Proceedings of the Second Joint EMBS/BMES Conference Houston TX, USA pp. 2625-2627, 2002.
Skadsberg ND, Coles Jr JA, Iaizzo PA: Electrophysiologic
assessment of right ventricular cardiac pacing sites employing non-contact
electrical mapping. International Journal of Bioelectromagnetism,
7: 1-4, 2005.
Laske T, Bonhoeffer P, Iaizzo P: Visualization
of transcatheter valve implantation in isolated human and porcine
hearts. 5th World Congress of Biomechanics. pp. 407-410, 2006.
Shrivastava D, Hanson T, Schlentz R, Gallagher W, Snyder C, DelaBarre
L, Prakash S, Iaizzo P, Vaughan JT. MR safety and
in vivo thermal characterization of an RF coil at 9.4T. ASME 2007
Summer Bioengineering Conference, June 20-24, 2007.
Letters
to the Editor
Lehmann-Horn F, Iaizzo PA: Myotonias and susceptibility to malignant hyperthermia. (Correspondence: Reply). British Journal of Anaesthesia 67:221-222, 1991.
Zink RS, Iaizzo PA: Convective warming therapy does not increase the risk of wound contamination in the operating room.; Anaesthesia Digest 3:9, 1993.
Iaizzo PA, Sessler: Skeletal muscle is responsible for heat production in porcine malignant hyperthermia (In Response: Letter to the Editor). Anesthesia and Analgesia 83:1134, 1996.
Iaizzo PA, Belani KG, Rosenberg H: VIIIth International workshop on malignant hyperthermia. The American Journal of Anesthesiology 24:40, 1997.
McLoon L, Iaizzo PA, Falkenberg J, Dykstra D: Doxorubicin chemomyectomy as a treatment for cervical dystonia (Reply: Letter to the Editor). Muscle and Nerve 22:652-653, 1999.
Educational Materials
Iaizzo PA: Anesthetic complications in patients with skeletal muscle disorders. Practical Reviews in Anesthesiology: Educational Reviews Audio Program, March 1997.
Iaizzo PA, Principal Investigator, The Visible Heart®: A New View Into the Heart. Demonstration CD, University of Minnesota and Medtronic Inc., November 1999.
Iaizzo PA, Principal Investigator, The Visible Heart® Viewer. Demonstration CD, University of Minnesota and Medtronic Inc., PACE Volume 23, April 2000.
Iaizzo PA, Principal Investigator, The Visible Heart® Viewer. Educational CD, Version 1.1, University of Minnesota and Medtronic Inc., December 2000.
"The Bear Evidence" A 50-minute film produced by Henson International Television, shown on National Geographic International, Fall 2001.
Iaizzo PA, Principal Investigator, The Visible Heart® CD Version 1.0, University of Minnesota and Medtronic, Inc., 2002.
"Waking up hibernating bears in Washington State" taped interview for segment, National Public Radio (NPR), Oct, 22, 2003. http://www.npr.org/rundowns/segment.php?wfId=1474914
Iaizzo PA, Principal Investigator, The Visible Heart® Viewer. Educational CD, Version 1.2, University of Minnesota and Medtronic, Inc., 2004.
Atlas of Human Cardiac Anatomy: a Web based textbook (http://www.vhlab.umn.edu/atlas),
2005.
Ellenbogen KA, Kay GN, Wilkoff BL (Editors). Clinical Cardiac Pacing
and Defibrillation, 2nd Edition. WB Saunders Company, Philadelphia,
PA, 2006. Visible Heart® pictures are featured in this book.
Iaizzo PA: U.S. History, 1865 to the Present. Educational
CD, Firm Foundations and New Perspectives, Osher Lifelong Learning
Institute, College of Continuing Education, University of Minnesota.
Presentation on “Technological and Medical Advancements,”
2006.
Iaizzo PA, Principal Investigator, The Atlas of
Human Cardiac Anatomy: Interactive Learning Tool Video Clips; CD
Version, University of Minnesota and Medtronic, Inc., 2002.
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