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Methods
Project Background Methods-Introduction The Preparation Langendorff Mode Four Chamber Working Mode The Apparatus Cardioplegia and Perfusates References

Langendorff, O. Untersuchungen am überlebenden Säugethierherzen. Pflügers Arch. ges. Physiol. 61, 291 (1895)Döring, HJ,

Dehnert H. The Isolated Perfused Warm-Blooded Heart according to Langendorff. Methods in Experimental Physiology and Pharmacology: Biological Measurement Techniques V. Biomesstechnik-Verlag March GmbH, West Germany. 1988.

Chinchoy E, Soule CL, Houlton AJ, Gallagher WJ, Hjelle MA, Laske TG, Morissett J, Iaizzo PA: Isolated four-chamber working swine heart model. Annals of Thoracic Surgery 70: 1607-1614, 2000.

Hill A, Coles JA Jr, Sigg DC, Laske, TG, Iaizzo PA: Images of the human coronary sinus ostium obtained from isolated working hearts. The Annals of Thoracic Surgery 76: 2108, 2003.

Hill AJ, Laske TG, Coles JA Jr, Sigg DC, Skadsberg ND, Vincent SA, Soule CL, Gallagher WJ, Iaizzo PA: In vitro studies of human hearts. The Annals of Thoracic Surgery 79: 168-177, 2005.

Coles JA Jr, Sigg DC, Iaizzo PA: The potential benefits of 1.5% hetastarch as a cardioplegia additive. Biochemical Pharmacology 69: 1553-1558, 2005.

Laske TG, Vincent SA, Skadsberg ND, Iaizzo PA: High pacing impedances: Are you overtorquing your leads? Pacing and Clinical Electrophysiology 28: 883-891, 2005.

Laske TG, Skadsberg ND, Iaizzo PA: A novel ex vivo heart model for the assessment of cardiac pacing systems. Journal of Biomechanical Engineering 127:894-898, 2005.

Hill AJ, Ahlberg SE, Wilkoff BL, Iaizzo PA: Dynamic obstruction to coronary sinus access: the Thebesian valve. Heart Rhythm 3:1240-1, 2006.

Sigg DC, Iaizzo PA: In vivo versus in vitro comparison of swine cardiac performance: Induction of cardiodepression with halothane. European Journal of Pharmacology, 543:97-107, 2006.

Anderson SE, Skadsberg ND, Laske TG, Benditt DG, Iaizzo PA: Variation in pacing impedance: impact of implant site and measurement method. PACE, 30:1076-82, 2007.

Anderson SE, Hill AJ, Iaizzo PA: Venous valves: unseen obstruction to coronary sinus. Journal of Interventional Cardiac Electrophysiology, 19:165-6, 2007.

Quill JL, Laske TG, Hill AJ, Bonhoeffer P, Iaizzo PA: Direct visualization of a transcatheter pulmonary valve implantation within the Visible Heart® – A Glimpse into the Future. Circulation, 116(22): 2007.

Hucker W, McCain ML, Laughner JI, Iaizzo PI, Efimov IR: Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction. Anatomical Record (in press) 2007.

 

 
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