Location:
between left atrium and left ventricle

Function:
ventricular diastole: open valve allows filling of left ventricle;
ventricular systole: closed valve prevents reflux from left ventricle to left atrium

Importance in cardiovascular diseases:
mitral valve stenosis, mitral valve insufficiency

Importance in device delivery:
ablation catheter entanglement during retrograde aortic approach for left ventricular and left atrial ablation